Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pax6  paired box 6   (Synonyms: 1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Pax-6)
Results	Reference
1*	J:76822 Anderson TR, Hedlund E, Carpenter EM, Differential Pax6 promoter activity and transcript expression during forebrain development. Mech Dev. 2002 Jun;114(1-2):171-5
1	J:63349 Behrens M, Venkatraman G, Gronostajski RM, Reed RR, Margolis FL, NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression. Eur J Neurosci. 2000 Apr;12(4):1372-84
1	J:309347 Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S, Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019 Mar;224(2):661-679
1	J:99491 Britanova O, Akopov S, Lukyanov S, Gruss P, Tarabykin V, Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-type-dependent expression in the developing mouse CNS. Eur J Neurosci. 2005 Feb;21(3):658-68
1	J:250493 Bunt J, Lim JW, Zhao L, Mason S, Richards LJ, PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep. 2015 May 29;5:10668
1	J:171293 Campbell GR, Baudhuin A, Vranizan K, Ngai J, Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Mol Cell Neurosci. 2011 Feb;46(2):548-61
1*	J:45299 Caric D, Gooday D, Hill RE, McConnell SK, Price DJ, Determination of the migratory capacity of embryonic cortical cells lacking the transcription factor Pax-6. Development. 1997 Dec;124(24):5087-96
1	J:98179 Caubit X, Tiveron MC, Cremer H, Fasano L, Expression patterns of the three Teashirt-related genes define specific boundaries in the developing and postnatal mouse forebrain. J Comp Neurol. 2005 May 23;486(1):76-88
1*	J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1	J:320740 Cobolli Gigli C, Scaramuzza L, De Simone M, Rossi RL, Pozzi D, Pagani M, Landsberger N, Bedogni F, Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development. Cereb Cortex. 2018 May 1;28(5):1846-1856
1*	J:65298 Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G, The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
1*	J:206224 Dixit R, Tachibana N, Touahri Y, Zinyk D, Logan C, Schuurmans C, Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation. Gene Expr Patterns. 2014 Jan;14(1):42-54
1	J:266522 Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF, The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6--> Tbr2--> Tbr1. Front Neurosci. 2018;12:571
1	J:158418 Endoh-Yamagami S, Karkar KM, May SR, Cobos I, Thwin MT, Long JE, Ashique AM, Zarbalis K, Rubenstein JL, Peterson AS, A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol. 2010 Apr 1;340(1):41-53
1*	J:48135 Fernandez AS, Pieau C, Reperant J, Boncinelli E, Wassef M, Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtle and frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Development. 1998 Jun;125(11):2099-111
1	J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58
1*	J:51693 Grimm C, Chatterjee B, Favor J, Immervoll T, Loster J, Klopp N, Sandulache R, Graw J, Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. Dev Genet. 1998;23(4):299-316
1*	J:25250 Grindley JC, Davidson DR, Hill RE, The role of Pax-6 in eye and nasal development. Development. 1995 May;121(5):1433-42
1*	J:74492 Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ, Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb;111(1-2):75-87
1	J:307953 Hu L, Chen Y, Yang CP, Huang Y, Song NN, Chen JY, Sun YL, Ding YQ, Lang B, Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice. Front Cell Dev Biol. 2021;9:645368
1	J:222296 Huang Y, Yu X, Sun N, Qiao N, Cao Y, Boyd-Kirkup JD, Shen Q, Han JD, Single-cell-level spatial gene expression in the embryonic neural differentiation niche. Genome Res. 2015 Apr;25(4):570-81
1	J:89119 Jones L, Lopez-Bendito G, Gruss P, Stoykova A, Molnar Z, Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
1	J:155751 Kang W, Wong LC, Shi SH, Hebert JM, The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis. J Neurosci. 2009 Nov 18;29(46):14571-80
1	J:225435 Laclef C, Anselme I, Besse L, Catala M, Palmyre A, Baas D, Paschaki M, Pedraza M, Metin C, Durand B, Schneider-Maunoury S, The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Hum Mol Genet. 2015 Sep 1;24(17):4997-5014
1*	J:70735 Lee CS, May NR, Fan CM, Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant. Dev Biol. 2001 Aug 1;236(1):17-29
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1	J:119448 Long JE, Garel S, Alvarez-Dolado M, Yoshikawa K, Osumi N, Alvarez-Buylla A, Rubenstein JL, Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation. J Neurosci. 2007 Mar 21;27(12):3230-43
1*	J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
1*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:177908 Muranishi Y, Terada K, Inoue T, Katoh K, Tsujii T, Sanuki R, Kurokawa D, Aizawa S, Tamaki Y, Furukawa T, An Essential Role for RAX Homeoprotein and NOTCH-HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination. J Neurosci. 2011 Nov 16;31(46):16792-807
1*	J:85332 Puelles L, Rubenstein JL, Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci. 2003 Sep;26(9):469-76
1	J:166617 Sakurai Y, Kurokawa D, Kiyonari H, Kajikawa E, Suda Y, Aizawa S, Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization. Dev Biol. 2010 Nov 15;347(2):392-403
1	J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356
1*	J:93057 Schuurmans C, Armant O, Nieto M, Stenman JM, Britz O, Klenin N, Brown C, Langevin LM, Seibt J, Tang H, Cunningham JM, Dyck R, Walsh C, Campbell K, Polleux F, Guillemot F, Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
1	J:168035 Shikata Y, Okada T, Hashimoto M, Ellis T, Matsumaru D, Shiroishi T, Ogawa M, Wainwright B, Motoyama J, Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages. Dev Biol. 2011 Jan 15;349(2):147-59
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*	J:1914 Walther C, Gruss P, Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 1991 Dec;113(4):1435-49
1	J:83385 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 2003 May 15;17(10):1271-80
1	J:213336 Yan X, Sabrautzki S, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Hrabe de Angelis M, Graw J, Peroxidasin is essential for eye development in the mouse. Hum Mol Genet. 2014 Nov 1;23(21):5597-614
1	J:160653 Zembrzycki A, Griesel G, Stoykova A, Mansouri A, Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. Neural Dev. 2007;2:8